Nature Collection

Nature journals

Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers

Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers

Abstract: ScRNA-seq has the ability to reveal accurate and precise cell types and states. Existing scRNA-seq platforms utilize bead-based technologies…
Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes

Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes

Abstract: The combination of in vivo extracellular recording and genetic-engineering-assisted optical stimulation is a powerful tool for the study of…
Controlled packing and single-droplet resolution of 3D-printed functional synthetic tissues

Controlled packing and single-droplet resolution of 3D-printed functional synthetic tissues

Abstract: 3D-printing networks of droplets connected by interface bilayers are a powerful platform to build synthetic tissues in which functionality…
Diagnosis and prognosis of myocardial infarction on a plasmonic chip

Diagnosis and prognosis of myocardial infarction on a plasmonic chip

Abstract: Cardiovascular diseases lead to 31.5% of deaths globally, and particularly myocardial infarction (MI) results in 7.4 million deaths per…
Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Abstract: Field-effect transistor (FET)-based biosensors allow label-free detection of biomolecules by measuring their intrinsic charges. The detection limit of these…
Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapy

Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapy

Abstract: Despite its growing promise in cancer treatment, ferrotherapy has low therapeutic efficacy due to compromised Fenton catalytic efficiency in…
Uniform nanoparticle vaccines

Uniform nanoparticle vaccines

Precise loading of diverse peptides for vaccination is enabled by a strategy for peptide–TLR7/8 conjugate self-assembly of uniform nanoparticles. The…
Nanocrystal facet modulation to enhance transferrin binding and cellular delivery

Nanocrystal facet modulation to enhance transferrin binding and cellular delivery

Abstract: Binding of biomolecules to crystal surfaces is critical for effective biological applications of crystalline nanomaterials. Here, we present the…
OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

  Abstract: Rewiring of energy metabolism and adaptation of mitochondria are considered to impact on prostate cancer development and progression.…
Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection

Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection

  Abstract: Although certain microbial lipids are toxins, the structural features important for cytotoxicity remain unknown. Increased functional understanding is…
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